Frank Detorre is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly vir... (Full plot summary below)
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Frank Detorre is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only Osmosis and Drix to put an end of Thrax's plans before Frank gets sick forever and Shane will become an orphan!
Leave your thoughts about Osmosis Jones.
| Chicago TribuneRobert K. ElderGets under your skin with laughs that are fast, slick and slippery and with visuals as vivid as anything this side of Demerol. |
| Seattle Post-IntelligencerSean AxmakerIt has zippy energy, visual imagination, inspired puns and all the fart jokes, booger gags, and vomit spews a 13-year-old could ask for... |
| Urban CinefileUrban Cinefile CriticsThe animated scenes directed by Piet Kroon and Tom Sito occupy most of the running time and are an imaginative and eyecatching tour of the human body. |
| Film Journal InternationalDoris ToumarkineIt does more than most films in amusingly illuminating things vital and scientific. |
| Wall Street JournalJoe MorgensternResuscitates the filmgoing summer with a vital jolt of pure piss and vinegar. |
| Zertinet MoviesSteven SnyderIt is funny, original, and even contains a genuine, good-natured theme. |
| Film Quips OnlineJohn R. McEwenI'd advise attendees of this film to go on an empty stomach, but if you're willing to endure the Farrellys' warped sense of humor and Murray's scratching, squirting, gas-passing antics, Osmosis Jones offers some lighthearted fun. |
| ViewLondonMatthew TurnerThe over-riding question with all comedies is 'Are there many laughs in it?' Luckily, the answer is yes - there are lots of great jokes, and not all of the scatological kind. |
| Hollywood.comKit BowenLeave it to the Farrelly brothers to once again gross us out. |
| Boxoffice MagazinePaul Clinton (Boxoffice)While the animated sequences are the most involving, the real-world scenes thud on the screen. |
